Costimulatory Molecules and Cytokine Production by T Lymphocytes in Common Variable Immunodeficiency Disease

Cytokine production by activated T cells in common variable immunodeficiency.

BACKGROUND Common variable immunodeficiency (CVID) is the most common symptomatic antibody deficiency. It is characterized by hypogammaglobulinemia, increased susceptibility to recurrent infections, autoimmunity, and malignancies. OBJECTIVES To determine whether patients with CVID have cytokine production defects after T-cell activation and to assess whether or not these are correlated with m...

cd40 ligand expression on stimulated t-helper lymphocytes in patients with common variable immunodeficiency

common variable immunodeficiency (cvid) is the most common symptomatic primary antibody deficiency, characterized by reduced serum immunoglobulins levels and increased susceptibility to recurrent pyogenic infections. in this study, we evaluated cd40 ligand expression on stimulated versus unstimulated t-helper lymphocytes of nine common variable immunodeficient patients in comparison with fiftee...

T Cell Abnormalities in Common Variable Immunodeficiency

1. Department of Laboratory Medicine, Imam Hassan Mojtaba Hospital, Alborz University of Medical Sciences, Karaj, Iran 2. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran 3. Primary Immunodeficiency Diseases Network (PIDNet), Universal Scientific Education and Research Network (USERN), Tehran, Iran 4. Department of Immunology...

Hodgkin's disease and common variable immunodeficiency.

CD40 ligand expression on stimulated T-helper lymphocytes in patients with common variable immunodeficiency.

Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody deficiency, characterized by reduced serum immunoglobulins levels and increased susceptibility to recurrent pyogenic infections. In this study, we evaluated CD40 ligand expression on stimulated versus unstimulated T-helper lymphocytes of nine Common variable immunodeficient patients in comparison with fiftee...